This article examines the necklaces used in the Afro-Cuban Rule of Orisha, more commonly known as Santería. This religion, created by African slaves brought to Cuba starting in the 16th century, combines aspects of Yoruba orisha worship and Spanish Catholicism. It allowed African religious beliefs and practices to survive despite the imposition of Catholic doctrine. One of the outcomes of this amalgamation is the practice of associating individual orishas (deities) with certain Catholic saints. Each orisha is represented by specific necklaces that incorporate particular bead forms, colors, and numbers.